| 发明名称 | Compositions of A-8R peptide | ||
| 摘要 | The present invention provides materials and methods useful to treat various sGCα1-expressing cancers. Materials include peptides which interfere with sGCα1's pro-survival functions, thereby resulting in apoptosis of sGCα1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits. | ||
| 申请公布号 | US9393254(B2) | 申请公布日期 | 2016.07.19 |
| 申请号 | US201314067084 | 申请日期 | 2013.10.30 |
| 申请人 | The University of Toledo | 发明人 | Shemshedini Lirim;Chen Shao-Yong;Cai Changmeng;Hsieh Chen-Lin |
| 分类号 | A61K38/10;A61K31/7048;C07K7/06;C07K7/08;A61K38/08;A61K38/00 | 主分类号 | A61K38/10 |
| 代理机构 | MacMillan, Sobanski & Todd, LLC | 代理人 | MacMillan, Sobanski & Todd, LLC |
| 主权项 | 1. A composition of matter comprising a peptide consisting of the amino acid sequence set forth in SEQ ID NO:1. | ||
| 地址 | Toledo OH US | ||