发明名称 |
Fluidic system for reagent delivery to a flow cell |
摘要 |
A fluidic system that includes a reagent manifold comprising a plurality of channels configured for fluid communication between a reagent cartridge and an inlet of a flow cell; a plurality of reagent sippers extending downward from ports in the manifold, each of the reagent sippers configured to be placed into a reagent reservoir in a reagent cartridge so that liquid reagent can be drawn from the reagent reservoir into the sipper; at least one valve configured to mediate fluid communication between the reservoirs and the inlet of the flow cell. The reagent manifold can also include cache reservoirs for reagent re-use. |
申请公布号 |
US9410977(B2) |
申请公布日期 |
2016.08.09 |
申请号 |
US201414453868 |
申请日期 |
2014.08.07 |
申请人 |
Illumina, Inc. |
发明人 |
Stone Michael;Verkade Drew |
分类号 |
B01L3/00;C12Q1/68;G01N35/10;G01N35/00;B01L3/02;G01N33/48 |
主分类号 |
B01L3/00 |
代理机构 |
Illumina, Inc. |
代理人 |
Murphy John T.;Moore Brent C.;Illumina, Inc. |
主权项 |
1. A fluidic system for delivering reagents from a reagent cartridge to a flow cell comprising:
a reagent manifold comprising a manifold body comprising a solid material through which a plurality of channels pass, wherein the plurality of channels is configured to fluidly connect a reagent cartridge to an inlet of a flow cell, wherein one or more of the channels in the manifold comprises a cache reservoir; a plurality of reagent sippers attached to the manifold body and extending downward from ports in the manifold, each of the reagent sippers configured to be placed into a reagent reservoir in a reagent cartridge so that liquid reagents can be drawn from a plurality of the reagent reservoirs into the sippers; at least one valve configured to mediate fluid communication through the plurality of reagent sippers, then through the channels and then through the inlet of the flow cell; and a detection apparatus configured to detect nucleic acid features in the flow cell. |
地址 |
San Diego CA US |