Antitumor composition containing a synergistic combination of an anthracycline derivative with a camptothecin derivate

摘要

The combination of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methansulfonyl daunorubicin or 4-demethoxy-N,N-bis(2-chloroethyl)-4'-methansulfonyl daunorubicin together with an antineoplastic topoisomerase I inhibitor yields preparations exhibiting anti-cancer effects. These preparations can be used in the treatment of tumors and especially 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methansulfonyl daunorubicin in the treatment of brain tumors.