发明名称 A process for the preparation of perindopril, and salts thereof using 2,5-dioxo-oxazolidine intermediate compounds
摘要 <p>A process for the preparation of a compound of formula (IV), or an ester or a salt thereof comprising 1) reacting a compound of formula (I), (wherein Ra represents C1-4 alkyl, Rb represents C1-4 alkyl and Rc represents C1-6 alkyl) with a compound of formula X2C=0 (wherein each X independently represents a leaving group) to give a compound of formula (II), (wherein Ra, Rb and Rc are as hereinbefore defined); and 2) reacting said compound of formula (II) with a compound of formula (III) (wherein Rd represents hydrogen or a protecting group).</p>
申请公布号 KR100694528(B1) 申请公布日期 2007.03.13
申请号 KR20047001019 申请日期 2002.07.23
申请人 发明人
分类号 C07D209/42;C07C227/18;C07C229/16;C07D263/44;C07K5/02;C07K5/062 主分类号 C07D209/42
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