发明名称 Methods of treating Parkinson's disease
摘要 Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as pharmacological chaperones for mutant forms of the beta-glucocerebrosidase. Methods of treatment involve providing therapeutically effective amounts of such compositions to subjects in need thereof.
申请公布号 US9415025(B2) 申请公布日期 2016.08.16
申请号 US201514977251 申请日期 2015.12.21
申请人 The Hospital for Sick Children;McMaster University 发明人 Mahuran Don J.;Tropak Michael B.;Buttner Justin D.;Blanchard Jan E.;Brown Eric D.
分类号 A61K31/58;A61K31/56;A61K31/553;A61K31/54;A61K31/137 主分类号 A61K31/58
代理机构 InHouse Patent Counsel, LLC 代理人 Wales Michele M.;InHouse Patent Counsel, LLC
主权项 1. A method of reducing the symptoms of Parkinson's Disease in a patient comprising administering to the patient ambroxol, ambroxol hydrochloride, or bromhexine, or a pharmaceutically acceptable salt thereof at a dose of 250-500 mg administered once, twice, three or four times a day.
地址 Toronto CA