INSULIN-LIKE GROWTH FACTOR II ANTISENSE OLIGONUCLEOTIDE SEQUENCES AND METHODS OF USING SAME TO MODULATE CELL GROWTH
摘要
This invention relates to oligonucleotides complementary to the IGF-II genes which modulate tumor cell growth in mammals. This invention is also related to methods of using such compounds in inhibiting the growth of tumor cells in mammals. This invention also relates to pharmaceutical compositions comprising a pharmaceutically acceptable excipient and an effective amount of a compound of this invention.
申请公布号
WO9955854(A3)
申请公布日期
2000.06.29
申请号
WO1999CA00323
申请日期
1999.04.23
申请人
GENESENSE TECHNOLOGIES INC.;WRIGHT, JIM, A.;YOUNG, AIPING, H.;LEE, YOON, S.