发明名称 |
SSA-56KDA POLYPEPTIDE AND ITS FRAGMENTS AND POLYNUCLEOTIDES ENCODING SAID POLYPEPTIDES AND THERAPEUTIC USES |
摘要 |
The invention concerns a novel SSA-56kDA polypeptide and its fragments, cDNA cloning and polynucleotides encoding said polypeptides, cloning and/or expression vectors including said polynucleotides, cells transformed by said vectors and specific antibodies directed against said polypeptides. The invention also concerns methods for detecting and/or assaying said polypeptides and polynucleotides, corresponding diagnostic kits, a method for screening ligands, a method for detecting anti-Ro/SSA-like autoantibodies, a method for purifying a human biological fluid capable of containing anti-Ro/SSA-like autoantibodies, and compounds for use as medicines for preventing and/or treating viral pathologies such as AIDS and autoimmune diseases, in particular systemic lupus erythematosus (SLE)and Sjögren syndrome. |
申请公布号 |
WO0188128(A1) |
申请公布日期 |
2001.11.22 |
申请号 |
WO2001FR00725 |
申请日期 |
2001.03.12 |
申请人 |
ISTAC;INSTITUT PASTEUR DE LILLE;BAHR, GEORGES;COCUDE, CECILE;CAPRON, ANDRE |
发明人 |
BAHR, GEORGES;COCUDE, CECILE;CAPRON, ANDRE |
分类号 |
A01K67/027;A61K31/7088;A61K35/16;A61K38/00;A61K38/16;A61K39/395;A61K48/00;A61P31/12;A61P31/18;A61P31/22;A61P37/00;A61P37/02;C07K5/06;C07K14/47;C07K16/18;C07K16/42;C12M1/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/564;G01N33/569;G01N33/576;G01N37/00 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|