ORGANIC COMPOUNDS AND THEIR USES

摘要

The present invention relates to methods of treating neoplasms, particularly involving brain tumors, including gliomas and glioblastomas, comprising the combination of a growth factor receptor inhibitor with a compound that inhibits the binding of the second mitochondria-derived activator of caspase (Smac) protein to inhibitor of apoptosis (IAPs) (IAP inhibitor), and one or more pharmaceutically active agents; pharmaceutical compositions comprising said combination; and a commercial package comprising said combination.