| 发明名称 |
METHOD FOR TREATING CARTILAGE DISORDERS |
| 摘要 |
The present invention relates to a method for the treatment of a cartilage disorder, including cartilage damaged by injury or degenerative cartilagenous disorders. The method involves contacting the cartilage with an IGF-1 analog with altered affinity for IGF-binding proteins (IGFBPs) or an IGFBP displacer peptide that prevents the interaction of an IGF with an IGFBP and does not bind to a human IGF receptor.
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| 申请公布号 |
US2009011988(A1) |
申请公布日期 |
2009.01.08 |
| 申请号 |
US20070929468 |
申请日期 |
2007.10.30 |
| 申请人 |
CHEN YVONNE MAN-YEE;CLARK ROSS G;COCHRAN ANDREA G;DUBAQUIE YVES;FIELDER PAUL J;FILVAROFF ELLEN;LOWMAN HENRY B;MORTENSEN DEBORAH L;ROBINSON IAIN C A F;SKELTON NICHOLAS J |
发明人 |
CHEN YVONNE MAN-YEE;CLARK ROSS G.;COCHRAN ANDREA G.;DUBAQUIE YVES;FIELDER PAUL J.;FILVAROFF ELLEN;LOWMAN HENRY B.;MORTENSEN DEBORAH L.;ROBINSON IAIN C.A.F.;SKELTON NICHOLAS J. |
| 分类号 |
A61K38/30;A61K38/00;A61K38/17;A61P19/00;C07K7/08;C07K14/47;C07K14/65 |
主分类号 |
A61K38/30 |
| 代理机构 |
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