发明名称 |
Combination of a prostaglandin receptor agonist and an MC1R receptor agonist for the treatment and/or prevention of pigmentation disorders |
摘要 |
A combination of compounds is described for the treatment and/or prevention of skin conditions linked to hypopigmentation. Also described, is a combination product that includes at least one prostaglandin receptor agonist and at least one MC1R receptor agonist, as a medicament for use simultaneously, separately or spread out over time for the treatment and/or prevention of skin conditions linked to hypopigmentation, such as vitiligo. |
申请公布号 |
US9364455(B2) |
申请公布日期 |
2016.06.14 |
申请号 |
US201214365851 |
申请日期 |
2012.12.17 |
申请人 |
GALDERMA RESEARCH & DEVELOPMENT |
发明人 |
Martel Philippe;Suzuki Itaru;Voegel Johannes;Andres Philippe;Rethore Sandrine |
分类号 |
A61K38/34;C07K14/68;A61K31/216;A61K45/06;A61K31/165;A61K31/192;A61K31/4178;A61K31/454;A61K38/33;A61K38/35 |
主分类号 |
A61K38/34 |
代理机构 |
Dentons US LLP |
代理人 |
Dentons US LLP |
主权项 |
1. A combination product comprising at least one prostaglandin receptor agonist and at least one MC1R receptor agonist, as a medicament for use simultaneously, separately or spread out over time for the treatment of dermatological conditions linked to hypopigmentation,
wherein the prostaglandin receptor agonist is present at a concentration of between approximately 0.001% and 1% by weight, relative to the total weight of a composition comprising the prostaglandin receptor agonist, and the MC1R receptor agonist is present at a concentration of between approximately 0.001% and 10% by weight, relative to the total weight of a composition comprising the MC1R receptor agonist. |
地址 |
Biot FR |