发明名称 Combination of a prostaglandin receptor agonist and an MC1R receptor agonist for the treatment and/or prevention of pigmentation disorders
摘要 A combination of compounds is described for the treatment and/or prevention of skin conditions linked to hypopigmentation. Also described, is a combination product that includes at least one prostaglandin receptor agonist and at least one MC1R receptor agonist, as a medicament for use simultaneously, separately or spread out over time for the treatment and/or prevention of skin conditions linked to hypopigmentation, such as vitiligo.
申请公布号 US9364455(B2) 申请公布日期 2016.06.14
申请号 US201214365851 申请日期 2012.12.17
申请人 GALDERMA RESEARCH & DEVELOPMENT 发明人 Martel Philippe;Suzuki Itaru;Voegel Johannes;Andres Philippe;Rethore Sandrine
分类号 A61K38/34;C07K14/68;A61K31/216;A61K45/06;A61K31/165;A61K31/192;A61K31/4178;A61K31/454;A61K38/33;A61K38/35 主分类号 A61K38/34
代理机构 Dentons US LLP 代理人 Dentons US LLP
主权项 1. A combination product comprising at least one prostaglandin receptor agonist and at least one MC1R receptor agonist, as a medicament for use simultaneously, separately or spread out over time for the treatment of dermatological conditions linked to hypopigmentation, wherein the prostaglandin receptor agonist is present at a concentration of between approximately 0.001% and 1% by weight, relative to the total weight of a composition comprising the prostaglandin receptor agonist, and the MC1R receptor agonist is present at a concentration of between approximately 0.001% and 10% by weight, relative to the total weight of a composition comprising the MC1R receptor agonist.
地址 Biot FR