发明名称 |
Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers |
摘要 |
The invention describes novel isolated, purified, 10,17-dihydroxy-docosahexaenoic acids, esters, derivatives and their preparation. |
申请公布号 |
US9364454(B2) |
申请公布日期 |
2016.06.14 |
申请号 |
US201213625865 |
申请日期 |
2012.09.24 |
申请人 |
The Brigham and Women's Hospital, Inc.;University of Southern California |
发明人 |
Serhan Charles N.;Petasis Nicos A.;Levy Bruce D. |
分类号 |
C07C59/00;A61K31/202;C07C59/42;C07C69/732 |
主分类号 |
C07C59/00 |
代理机构 |
Christensen Fonder P.A. |
代理人 |
Christensen Fonder P.A. ;Fairman Colin |
主权项 |
1. A purified compound of formula (I), (III), (IV), (V), or (VIII): wherein R is a hydrogen atom, an alkyl group, or a pharmaceutically acceptable salt; P1 and P2 are each, individually, a hydrogen atom or a protecting group and * indicates bonds are, independently, in the R or S configuration. |
地址 |
Boston MA US |