发明名称 |
Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging |
摘要 |
Functional PLA-PEG copolymers, the nanoparticles thereof, their preparation and use for targeted drug delivery and imaging The present invention concerns novel functional PEG-PLA containing copolymers, the nanoparticles containing the same, their process of preparation and their use for site specific targeted drug delivery and imaging.; |
申请公布号 |
US9364444(B2) |
申请公布日期 |
2016.06.14 |
申请号 |
US201314381197 |
申请日期 |
2013.02.28 |
申请人 |
SANOFI |
发明人 |
Bazile Didier;Couvreur Patrick;Lakkireddy Harivardhan Reddy;Mackiewicz Nicolas;Nicolas Julien |
分类号 |
A61K47/30;A61K9/51;A61K47/48;C07D249/04;C08G63/664;C08G63/685;A61K31/337;C08G63/91 |
主分类号 |
A61K47/30 |
代理机构 |
McDonnell Boehnen Hulbert & Berghoff LLP |
代理人 |
McDonnell Boehnen Hulbert & Berghoff LLP |
主权项 |
1. A compound of formula (A)where:
PLA represents a polylactic acid rest; PEG represents a polyethylene glycol rest; the linker PEG′ is a polyethylene glycol rest; and Ligand is a functional ligand rest. |
地址 |
Paris FR |