RADIOACTIVE AGENT SYNTHESIS DEVICE AND METHOD

摘要

In a reaction between a biomolecule and a radioactive agent precursor, the amount of a component of a radioactive agent precursor before the reaction and the amount of a component contained in a reaction mixture in a reaction process in which the reaction is performed at a predetermined biomolecule concentration are measured, a reaction rate constant is calculated from the information of the obtained amounts of the components, a reaction rate constant when the biomolecule concentration is changed is calculated, a reaction time, a specific radioactivity, and a radioactivity level of an objective substance at each biomolecule concentration are predicted, and synthesis is performed under a reaction condition under which the highest specific radioactivity is obtained among the reaction conditions satisfying the synthesis requirements.

主权项

1. A radioactive agent synthesis device, characterized by comprising:
a reaction vessel in which at least a radioactive agent precursor solution and a protein solution are placed and a synthesis reaction is performed; a measurement section which measures the amount of a component of a radioactive agent precursor before the reaction and the amount of a component of a reaction mixture in the middle of the reaction; a processing section which performs synthesis processing including processing in which a reaction rate constant is calculated from the measurement information of the amounts of the components, a reaction rate constant when a biomolecule concentration is changed is calculated, and a reaction time, a specific radioactivity, and a radioactivity level of an objective substance at each biomolecule concentration are calculated; a display section which displays the result of the synthesis processing by the processing section; and an input section from which a condition for the synthesis processing is input, wherein the processing section uses the result of the first synthesis processing obtained by the processing section as a synthesis condition for second synthesis processing to be performed thereafter along with the condition to be input from the input section.