| 主权项 |
1. A compound having the chemical structure shown in Formula IV wherein R is H, alkyl, acetyl, or heteroalkyl; R1 is H, alkyl, acetyl, or heteroalkyl; R8 and R9 are, independently of one another, H, —OH, acetyl, —C(O)NH2, alkyl, cycloalkyl, hereterocycloalkyl, aryl, or heteroaryl, wherein any one of the alkyl, cycloalkyl, hereterocycloalkyl, aryl, or heteroaryl groups is optionally substituted with one or more of —OH, —NO2, —NH2, —NR6R7, carbonyl, alkoxy, alkyl, —OCX3, —OCHX2, —OCH2X, or halogen, or both R8 together form a carbonyl; and R10 is cycloalkyl, aryl, or heteroaryl, any of which is optionally substituted with one or more of —OH, —C(O)NH2, —C(O)CH3, —NO2, —NH2, —NR6R7, carbonyl, alkyl, alkoxy, alkylalkoxy, alkoxylalkoxy, halogenated alkoxyl, cycloalkyl, heterocycloalkyl, heteroarylcarbonyl, aryl, heteroaryl, —OCX3, —OCHX2, —OCH2X, —OSO2CH3, or -tosyl; R6 and R7 are, independently, H, alkyl, —SO2CH3, —C(O)CH3, or —C(O)NH2; X is independently H or halogen; and n is 2 or 3. |
