A preventive and therapeutic vaccine for (helicobacter pylori)-associated diseases

摘要

The present invention relates to a preventive and therapeutic vaccine for H. pylori-associated diseases which comprises an active ingredient of a chimeric protein consisting of adhesin, an antigenic protein of H. pylori and A2 and B subunits of Vibrio cholerae toxin as an adjuvant. Since the adhesin/CTXA2B chimeric protein can induce specific antibodies neutralizing H. pylori, it can be used as an active ingredient of diagnostic kit for H. pylori infection and preventive or therapeutic vaccine for H. pylori-associated diseases as well.