| 摘要 |
<p>Compositions and methods are provided to control the release of relatively l ow molecular weight therapeutic species through hydrogels by first dispersing o r dissolving such therapeutic species within relatively hydrophobic rate modifying agents to form a mixture. The mixture is formed into microparticle s that are dispersed within bioabsorbable hydrogels, so as to release the wate r soluble therapeutic agents in a controlled fashion. Methods of using the compositions of the present invention in therapeutic systems are also provid ed.</p> |
