发明名称 |
Practical syntheses of chiral trans-3, 4-disubstituted piperidines and the intermediates |
摘要 |
A new method for the preparation of chiral 4-substituted 2-piperidinones, trans-3,4-disubstituted 2-piperidinones, and trans-3,4-disubstituted piperidines is invented. Chiral paroxetine can be obtained from a chiral trans-3,4-disubstituted piperidine intermediate in high purity and good selectivity.
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申请公布号 |
US2002169323(A1) |
申请公布日期 |
2002.11.14 |
申请号 |
US20020156499 |
申请日期 |
2002.05.28 |
申请人 |
LIU LEE TAI;HUANG HSIANG-LING;HONG PAO-CHIUNG;CHEN SHYH-FONG |
发明人 |
LIU LEE TAI;HUANG HSIANG-LING;HONG PAO-CHIUNG;CHEN SHYH-FONG |
分类号 |
C07C233/11;C07C235/34;C07D211/22;C07D211/76;C07D405/12;(IPC1-7):C07D211/40;C07D211/54 |
主分类号 |
C07C233/11 |
代理机构 |
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