发明名称 Transdermal methotrexate preparations
摘要 A methotrexate-containing transdermal preparation effective for rheumatoid arthritis comprises an organic amine. The organic amine may preferably be an alkonolamine such as monoethanolamine, diethanolamine, triethanolamine or diisopropanolamine, or an alkylamine such as ehtylamine, diethylamine or triethylamine. The transdermal preparation is, for example, a plaster, a cataplasm, an ointment, a cream or a lotion.
申请公布号 US6485740(B1) 申请公布日期 2002.11.26
申请号 US20000525747 申请日期 2000.03.14
申请人 YUTOKU PHARMACEUTICAL IND., CO., LTD. 发明人 TOMINAGA KENJI;HAMADA TAKAAKI
分类号 A61K31/519;A61K47/18;(IPC1-7):A61F13/00;A61F13/02 主分类号 A61K31/519
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