ELECTROCHEMICALLY AND OPTICALLY MONITORING CLEAVING ENZYME ACTIVITY

摘要

A marker molecule for monitoring cleaving enzyme activity is disclosed. The marker molecule includes a protein, a peptide, or an oligonucleotide. A co-factor is conjugated to the protein, the peptide, or the oligonucleotide, thereby forming a co-factor labeled protein, a co- factor labeled peptide, or a co-factor labeled oligonucleotide. The co-factor is adapted to produce an enzymatic signal that is at least one of electrochemically and optically detectable.