| 发明名称 |
Isethionate salt of a selective CKD4 inhibitor |
| 摘要 |
Disclosed are polymorphs of the isethionate salt of 6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one, which is a selective cyclin-dependent kinase 4 (CDK4) inhibitor useful for treating inflammation and cell proliferative diseases such as cancer and restenosis.
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| 申请公布号 |
US7345171(B2) |
申请公布日期 |
2008.03.18 |
| 申请号 |
US20040884927 |
申请日期 |
2004.07.06 |
| 申请人 |
WARNER-LAMBERT COMPANY LLC |
发明人 |
BEYLIN VLADIMAR G.;BLACKBURN ANTHONY CLYDE;ERDMAN DAVID THOMAS;TOOGOOD PETER LAURENCE |
| 分类号 |
C07D471/04;A61P31/12;A61P35/00;C07D487/04 |
主分类号 |
C07D471/04 |
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