Connective-tissue-based or dermal-tissue-based grafts/implants

摘要

The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.

主权项

1. An implant comprising:
a matrix of allogeneic or xenogenic tissue formed from a tissue slurry that has been dried to a shape, either wherein the shape includes a cavity, a pouch, or a hole, or wherein the implant further comprises a post, a hook, or a suture, and wherein said implant has the property of holding said shape during rehydration and handling.