发明名称 Combination therapy using anti-EGFR antibodies and anti-hormonal agents
摘要 The invention relates to a combination therapy for the treatment of tumors and tumor metastases, preferably breast and prostate tumors, comprising administration of anti-EGFR (Her1) antibodies and anti-hormonal agents, optionally together with cytotoxic/chemotherapeutic agent. The method and the pharmaceutical compositions comprising said agents can result in a synergistic potentiation of the tumor cell proliferation inhibition effect of each individual therapeutic agent, yielding more effective treatment than found by administering an individual component alone.
申请公布号 US2007202101(A1) 申请公布日期 2007.08.30
申请号 US20070789883 申请日期 2007.04.26
申请人 MERCK PATENT GMBH 发明人 ROSEN OLIVER;HARSTRICK ANDREAS
分类号 A61K39/395;A61K45/00;A61K31/00;A61K31/56;A61K31/565;A61K38/00;A61K38/09;A61P35/00;A61P35/04;A61P43/00;C07K16/28;C07K16/46 主分类号 A61K39/395
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