发明名称 |
Chimeric soluble hyper il-11 and use thereof |
摘要 |
The present invention concerns a new designer cytokine termed H11, which is constructed by fusion of two soluble components, soluble interleukin 11 receptor (sIL-11 R) and interleukin 11 (IL-11) using their natural sequence and its use for the production of a medicament for treating or preventing a disease selected from the group consisting of a proliferative disease, a cytopathy, radiation damage, an IL-11 dependent inflammatory disorder, IL-11 dependent degenerative disorder and IL-11 dependent or mediated soft tissue disorder.
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申请公布号 |
US2009010872(A1) |
申请公布日期 |
2009.01.08 |
申请号 |
US20050596753 |
申请日期 |
2005.05.20 |
申请人 |
MACKIEWICZ ANDRZEJ;DAMS-KOZLOWSKA HANNA;ROSE-JOHN STEFAN |
发明人 |
MACKIEWICZ ANDRZEJ;DAMS-KOZLOWSKA HANNA;ROSE-JOHN STEFAN |
分类号 |
A61K45/00;A61K35/12;A61K38/00;A61K38/20;A61P43/00;C07K14/00;C07K14/54;C07K14/715;C07K16/18;C12N1/19;C12N1/20;C12N5/06;C12N15/00;C12N15/11;C12N15/62;C12N15/87;C12P21/04 |
主分类号 |
A61K45/00 |
代理机构 |
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地址 |
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