发明名称 AZAINDAZOLE COMPOUNDS AND METHODS OF USE
摘要 Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
申请公布号 CA2687766(C) 申请公布日期 2016.06.28
申请号 CA20082687766 申请日期 2008.05.21
申请人 CHEMOCENTRYX, INC. 发明人 ZHANG, PENGLIE;PENNELL, ANDREW M. K.;WRIGHT, JOHN J. KIM;CHEN, WEI;LELETI, MANMOHAN R.;LI, YANDONG;LI, LIANFA;XU, YUAN;GLEASON, MARK M.;ZENG, YIBIN;GREENMAN, KEVIN LLOYD
分类号 C07D471/04;A61K31/496;A61L27/54;A61L31/16;A61P29/00 主分类号 C07D471/04
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