发明名称 |
Enzymatic process for preparing cephalosporin derivatives |
摘要 |
A process for preparing cephalosporanic acid derivatives comprises the steps of enzymatically converting a 3-thiolated cephalosporin C compound of formula III: into a 3-thiolated-alpha-ketoadipyl-7-aminocephalosporanic acid derivative of formula IV: wherein R is a heterocyclic group comprising at least a nitrogen atom. Compounds of formula IV are used in the preparation of cephalosporin C antibiotics and derivatives thereof. |
申请公布号 |
AU2002316862(A1) |
申请公布日期 |
2002.11.05 |
申请号 |
AU20020316862 |
申请日期 |
2002.04.18 |
申请人 |
BIOFERMA MURCIA, S.A. |
发明人 |
ALVARO SANCHEZ-FERRER;FRANCISCO GARCIA-CARMONA;JOSE ANICETO LOPEZ-MAS |
分类号 |
C12P35/06;C07D498/04;C07D501/00;C07D501/04;C07D501/12;C07D501/14;C07D501/18;C07D501/36;C12P35/02 |
主分类号 |
C12P35/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|