发明名称 |
Process for preparing 4-aminomethyl-3-alkoxyiminopyrrolidine methanesulfonate |
摘要 |
The present invention relates to a process for the preparation of 4-aminomethyl-3-alkoxyiminopyrrolidine methane-sulfonate, a key intermediate of quinolone antibiotics. According to the process of the present invention, the total number of steps has been shortened to 2-3 steps, the solid separation is not required, and the use of costly chemicals, particularly (BOC)<SUB>2</SUB>O (t-butoxycarbonyl anhydride), several organic solvents and reactants, is eliminated. |
申请公布号 |
US7271272(B2) |
申请公布日期 |
2007.09.18 |
申请号 |
US20050548324 |
申请日期 |
2005.09.07 |
申请人 |
LG LIFE SCIENCES LTD. |
发明人 |
HWANG, GYO-HYUN;KIM, YEONG-DAE;NAM, HYUN;CHANG, JAY-HYOK;SHIN, HYUN-IK;KIM, YOUNG-KEUN;LEE, KYUNG HEE;LEE, JAE SUNG;NOH, HYUN-KUK |
分类号 |
C07D207/04;C07D207/22 |
主分类号 |
C07D207/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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