| 摘要 |
This invention relates to a process for the preparation of compounds of formula (I) wherein: R2 is C1-6 straight- or branched-chain alkylthio, C1-6alkyl, C1-6haloalkyl, CH2SR5, C1-6alkoxy, C1-6haloalkoxy, or halogen; or an N-linked imidazole, pyrazole, 1,2,3,4-tetrazole, 1,2,3-triazole or 1,2,4-triazole ring which ring systems are optionally substituted by one or more groups selected from halogen, C1-6alkyl, C1-6haloalkyl or C1-6 straight- or branched-chain alkylthio; R3 i s C1-6 straight- or branched-chain haloalkyl, C1-6 straight- or branched-chain alkyl, C1-6alkoxy, C1-6haloalkoxy, halogen, C1-6 straight- or branched-chain alkylthio or nitro; or an N-linked imidazole, pyrazole, 1,2,3,4-tetrazole, 1,2,3-triazole or 1,2,4-triazole ring which rin g systems are optionally substituted by one or more groups selected from halogen, C1-6alkyl, C1-6haloalkyl or C1-6 straight- or branched-chain alkylthio; R4 is hydrogen, C1-6 straight- or branched-chain haloalkyl, C1-6 straight- or branched-chain alkyl, C1-6alkoxy, C1-6haloalkox y, halogen, C1-6 straight- or branched-chain alkylthio; or a 5- or 6-membered heterocyclic ring (which may be unsaturated or partially saturated) containing 1 to 3 hetero atoms selected from oxygen, nitrogen and sulphur, optional substituted by halogen, C1-6haloalkyl, C1- 6alkyl, C1-6haloalkoxy, C1-6alkoxy, SO n R5, nitro or cyano; or R3 and R4 together with the carbon atoms to which they are attached, form a 5- to 7-membered saturated or unsaturated heterocyclic ring containing up to three ring heteroatoms selected from nitrogen, oxygen and sulfur, which ring is optionally substituted by one or more groups selected from halogen, nitro, C1-6 straight- or branched-chain alkylthio, C1-4alkyl, C1-4alkoxy, C1-4haloalkyl, C1-4haloalkoxy, =O and =NO-R5; and R5 represents C1-6 straight- or branched-chain alkyl; and n represents zero, one or two; which process comprises the reaction of a compound of formula (II); wherein R1 is C1-6 straight- or branched-chain alkyl, R2, R3 and R4 are as hereinbefore defined, with a compound of formula (III); in an aprotic solvent in the presence of a base.
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