The invention relates to a pharmaceutical composition and oral dosage forms comprising a DAC inhibitor in combination with an enhancer to promote absorption of the DAC inhibitor at the GIT cell lining. The enhancer can be a medium chain fatty acid or derivative thereof having a carbon chain length of from 6 to 20 carbon atoms. In certain embodiments, the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.
申请公布号
WO2007146234(A8)
申请公布日期
2008.09.12
申请号
WO2007US13693
申请日期
2007.06.11
申请人
MERRION RESEARCH II LIMITED;LEONARD, THOMAS, W.;O'TOOLE, EDEL;FEENEY, ORLAGH