主权项 |
1. A compound of formula (I) wherein the ring A is 6-membered aryl; n is an integer of from 0 to 3; m is an integer of from 0 to 2; p is an integer of from 0 to 3; each R1 is independently selected from the group consisting of C1-C6 alkyl; C1-C6 alkoxy; OH; halogen; and R5R6N; R2 is selected from H and C1-C6 alkyl; each R3 is independently selected from C1-C6 alkyl; each R4 is independently selected from NO2; halogen; C1-C6 alkyl and C1-C6 alkoxy; R5 and R6 are independently selected from H and C1-C6 alkyl; wherein any alkyl is optionally substituted with one or several halogen atoms; and the ring of formula (III) is a ring of formula (IIIa), (IIIb), (IIIc), (IIId), or (IIIe): wherein in formula (IIIa), X is NH or O, and Y is N or CH, in formula (IIIb), X is N or CH, and Y is NH or O, in formula (IIIc), X is N, and Y is N or CH, in formula (IIId), X is N or CH, and Y is N or CH, and in formula (IIIe), X is N or CH, and Y is N or CH, or a pharmaceutically acceptable salt thereof. |