| 发明名称 | Synthesis of syrbactin proteasome inhibitors | ||
| 摘要 | The disclosure relates generally to methods for the preparation of a family of natural compounds, the syrbactins and their analogs. | ||
| 申请公布号 | US9359309(B2) | 申请公布日期 | 2016.06.07 |
| 申请号 | US201514981857 | 申请日期 | 2015.12.28 |
| 申请人 | The Regents of the University of California | 发明人 | Pirrung Michael C. |
| 分类号 | C07D273/02;C07D285/00;C07D245/02 | 主分类号 | C07D273/02 |
| 代理机构 | Gavrilovich, Dodd & Lindsey LLP | 代理人 | Baker, Jr. Joseph R.;Gavrilovich, Dodd & Lindsey LLP |
| 主权项 | 1. A method to synthesize a compound 1 having the structure of: comprising reactions (a)-(d): wherein, R3 is a (C1-C6) alkyl, and Boc is a tert-butyloxycarbonyl protecting group. | ||
| 地址 | Oakland CA US | ||