发明名称 |
USE OF 6-HYDROXY-2-PYRIDONES AND DERIVATIVES THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION THAT ACTS BY INHIBITING THE HUMAN URIDINE PHOSPHORYLASE ENZYME |
摘要 |
The present invention describes the use of at least one compound of formula I or II or pharmaceutically acceptable salts thereof, for preparing a pharmaceutical composition that acts by inhibiting the phosphorylase uridine enzyme. Specifically, the present invention comprises the use of the said compounds for preparing a pharmaceutical composition that acts by inhibiting the human phosphorylase uridine enzyme, which can be optionally used in combination with at least one antineoplastic, wherein said inhibition increases the effectiveness of antineoplastic and decreases the side effects caused by the administration of antineoplastics. |
申请公布号 |
EP3042657(A1) |
申请公布日期 |
2016.07.13 |
申请号 |
EP20140842693 |
申请日期 |
2014.09.02 |
申请人 |
UNIÃO BRASILEIRA DE EDUCAÇAO E ASSISTÊNCIA- MANTENEDORA DA PUCRS |
发明人 |
BASSO, LUIZ AUGUSTO;MACHADO, PABLO;RENCK, DAIANA;SANTOS, DIÓGENES SANTIAGO |
分类号 |
A61K31/4412;A61K31/505;A61P35/00 |
主分类号 |
A61K31/4412 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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