Topical pharmaceutical composition comprising nanonized silver sulfadiazine

摘要

The invention relates to a topical pharmaceutical composition for burn treatment and microbial infections on human beings or animals. The pharmaceutical composition comprises 0.1% w/w to 1.0% w/w of an antimicrobial drug, i.e., silver sulfadiazine and 0.2% w/w antiseptic, i.e., chlorhexidine gluconate, wherein silver sulfadiazine is in nanonized form.

主权项

1. A topical pharmaceutical composition consisting of 0.1% w/w to 1.0% w/w silver sulfadiazine, 0.2% w/w chlorhexidine gluconate, and one or more pharmaceutically acceptable excipients wherein silver sulfadiazine has a Z-average particle size between 150 nm and 500 nm.