发明名称 CHIMERIC FLAVIVIRUS VACCINES
摘要 <p>A chimeric live, infectious, attenuated virus, containing a yellow fever virus, in which the nucleotide sequence for a prM-E protein is either deleted, truncated, or mutated, so that functional prM-E protein is not expressed, and integrated into the genome of the yellow fever virus, a nucleotide sequence encoding a prM-E protein of a second, different flavivirus, so that the prM-E protein of the second flavivirus is expressed.</p>
申请公布号 WO1998037911(A1) 申请公布日期 1998.09.03
申请号 US1998003894 申请日期 1998.03.02
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