发明名称 |
STABILIZATION OF CONJUGATES COMPRISING A THIOUREA LINKER |
摘要 |
The present invention discloses a composition containing a conjugate comprising two moieties covalently linked by a thiourea linker and thiourea or a derivative thereof in free form. It also relates to a method for stabilizing a conjugate comprising two moieties covalently linked by a thiourea linker is described the method comprising the steps of providing the conjugate, adding thereto thiourea or a derivative thereof in free form and thereby stabilizing the conjugate and to the use of a composition containing a conjugate comprising two moieties covalently linked by a thiourea linker and thiourea or a derivative thereof in free form. |
申请公布号 |
CA2645309(C) |
申请公布日期 |
2016.07.19 |
申请号 |
CA20082645309 |
申请日期 |
2008.11.27 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BLIND, RENE;FINK, GERHARD;HOESS, EVA;KYTZIA, HANS-JOACHIM |
分类号 |
C09K15/26 |
主分类号 |
C09K15/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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