发明名称 |
NOVEL beta -LACTAMASE AND DD-PEPTIDASE INHIBITORS |
摘要 |
The invention provides novel beta -lactamase inhibitors, which are structurally unrelated to the natural product and semi-synthetic beta -lactamase inhibitors presently available, and which do not possess beta -lactam pharmacophore. These new inhibitors are fully synthetic, allowing ready access to a wide variety of structurally related analogs. Certain embodiments of these new inhibitors also bind bacterial DD-peptidases, thus potentially acting both as beta -lactamase inhibitors and as antibiotics.
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申请公布号 |
WO9933850(A8) |
申请公布日期 |
1999.09.10 |
申请号 |
WO1998US27518 |
申请日期 |
1998.12.23 |
申请人 |
METHYLGENE, INC.;WESLEYAN UNIVERSITY;BESTERMAN, JEFFREY, M.;RAHIL, JUBRAIL;PRATT, REX |
发明人 |
BESTERMAN, JEFFREY, M.;RAHIL, JUBRAIL;PRATT, REX |
分类号 |
A61K31/662;A61P31/04;A61P43/00;C07F9/09;C07F9/40;C07F9/6571;C07F9/6574;(IPC1-7):C07F9/40;A61K31/66;C07F9/657 |
主分类号 |
A61K31/662 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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