| 摘要 |
<p>The present invention relates to the detection of genetic polymorphisms in gene encoding xenobiotics metabolizing enzymes CYP1A1, CYP2D6, CYP3A4, and NAT2. In particular, the present invention relates to a method of detecting genetic variation in individuals by amplifying the locus of interest, hybridizing the resulting amplification product with allele-specific-oligonucleotides (ASOs), and visualizing the results. Such a method is in the field of diagnostics, pharmacogenetics, therapeutics, and drug metabolism.</p> |
