发明名称 |
NOVEL DERIVATIVES OF CYCLOALCANODIONES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACOLOGICAL APPLICATIONS |
摘要 |
<p>New cycloalkanedione derivatives that are serotonin (5-hydroxytriptamine, 5-HT) 5-HT1A receptor subtype agonists and, consequently, they are useful in the treatment of pathological states for which an agonist of these receptors is indicated. <??>They are particularly useful as neuroprotective agents, of special interest in the treatment and prophylaxis of cerebral damage produced by traumatic or ischemic stroke. <??>In general terms, said cycloalkanedione derivatives correspond to formula I: <CHEM></p> |
申请公布号 |
EP1544201(A1) |
申请公布日期 |
2005.06.22 |
申请号 |
EP20030784210 |
申请日期 |
2003.07.29 |
申请人 |
CEPA SCHWARZ PHARMA S.L. |
发明人 |
DEL RIO ZAMBRANA, JOAQUIN;FRECHILLA MANSO, DIANA;LOPEZ RODRIGUEZ, LUZ, M.;BENHAMU SALAMA, BELLINDA;FUENTES CUBERO, JOSE, ANGEL;DELGADO WALLACE, MERCEDES |
分类号 |
C07D277/20;A61K31/34;A61K31/4188;A61K31/427;A61K31/429;A61P9/00;A61P9/10;A61P43/00;C07D277/34;C07D417/12;C07D487/04;C07D513/04;(IPC1-7):C07D487/04;C07D277/04;A61K31/418;A61K31/381 |
主分类号 |
C07D277/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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