| 发明名称 | Immediate release composition resistant to abuse by intake of alcohol | ||
| 摘要 | The present invention provides immediate release pharmaceutical compositions for oral administration that are resistant to abuse by intake of alcohol. | ||
| 申请公布号 | US9358295(B2) | 申请公布日期 | 2016.06.07 |
| 申请号 | US201514656016 | 申请日期 | 2015.03.12 |
| 申请人 | EGALET LTD. | 发明人 | Tygesen Peter Holm;Oevergaard Jan Martin;Oestman Joakim |
| 分类号 | A61K9/46;A61K9/16;A61K31/44;A61K31/16;A61K31/485;A61K31/167;A61K9/28;A61K9/20;A61K47/10;A61K47/02;A61K47/12 | 主分类号 | A61K9/46 |
| 代理机构 | Foley & Lardner LLP | 代理人 | Foley & Lardner LLP |
| 主权项 | 1. An immediate release pharmaceutical composition resistant to alcohol-induced dose dumping, consisting of a single polymer matrix optionally provided with a coating, wherein the single polymer matrix has one or more drug substances dispersed therein and comprises (i) from about 30% to about 95% w/w of one or more polyglycols having a molecular weight of from about 900 to about 17,000 Daltons and (ii) one or more effervescent agents, and is resistant to alcohol-induced dose dumping. | ||
| 地址 | London GB | ||