CONCISE SYNTHESIS OF UREA DERIVATIVES OF AMPHOTERICIN B
摘要
Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti -fungal activity. Certain of the derivatives are C16 urea derivatives and C16 carbamate derivatives of AmB. Also provided are methods of making the AmB derivatives.
申请公布号
WO2016112260(A1)
申请公布日期
2016.07.14
申请号
WO2016US12602
申请日期
2016.01.08
申请人
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS