THIOFORMAMIDE DERIVATIVES

摘要

2073240 9110652 PCTABS00006 Thioformamide derivatives of formula (I), in which R represents alkyl, Y represents methylene, ethylene or a direct bond, A represents optionally substituted phenyl or heterocyclyl and: R1 represents hydrogen, and R2 represents an N-alkylsulphonyl- or N-phenylsulphonyl-N'-alkylamidino or an aryl- or alkylsulphonyl group; R1 and R2 both independently represents alkyl- or aryl-sulphonyl groups; or R1 and R2 form together with the nitrogen atom a 3,5-dioxomorpholino group or analogue thereof; and salts thereof possess pharmacological activity and are also useful in inhibiting head hair loss.