| 摘要 |
<p>This invention relates to controlled release compositions comprising (i) a matrix comprising starch having been processed under shear at temperatures of about 80 °C to about 240 °C in a closed volume wherein the water content of said matrix was maintained at about 5 % to about 45 % by weight based on the starch/water mix and (ii) an active ingredient, preferably a pharmaceutically active ingredient, wherein said matrix is in intimate contact with said active ingredient and wherein said matrix and pharmaceutically active ingredient are present in amounts sufficient to control the release of the pharmaceutically active ingredient in an effective dose.</p> |
