发明名称 |
Method of screening a peptide library |
摘要 |
The instant invention provides a library of bio-oligomers of defined size and known composition, in which the library contains all of the possible sequences of the bio-oligomers, and a method of synthesis thereof. The bio-oligomers of the library may be peptides, nucleic acids, or a combination of the foregoing. The instant invention also provides methods to identify bio-oligomers from a library that demonstrate desired characteristics such as binding, bioactivity and catalytic activity. Thus the instant invention provides a unique and powerful method to identify a useful bio-oligomer sequences from a library more quickly than current state-of-the-art technology allows. Effector molecules for use in treatment or diagnosis of disease are also provided.
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申请公布号 |
US5510240(A) |
申请公布日期 |
1996.04.23 |
申请号 |
US19930014979D |
申请日期 |
1993.02.08 |
申请人 |
THE ARIZONA BOARD OF REGENTS |
发明人 |
LAM, KIT S.;SALMON, SYDNEY E. |
分类号 |
A61K38/00;A61K38/02;A61K38/22;A61K39/00;A61K47/48;C07H21/00;C07K1/04;C07K1/06;C07K7/06;C07K7/08;C07K14/575;C07K14/70;C07K14/705;C07K14/82;C07K16/00;C07K17/00;C07K17/02;C07K17/08;C12N9/00;C12N15/00;C12N15/09;C12N15/10;C12P21/02;C12Q1/00;C12Q1/68;C12R1/91;C40B40/06;C40B40/10;G01N33/53;G01N33/531;G01N33/545;G01N33/68;(IPC1-7):C12Q1/00;G01N33/566;G01N33/543;C07K1/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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