COMPOSITION FOR THE INTRODUCTION OF NUCLEIC ACIDS COMPLEXES INTO HIGHER EUKARYOTIC CELLS
摘要
The composition is for the transfection of highr eukaryotic cells with a complex of nucleic acid and a substance having affinity to nucleic acid, which eventually is connected to an internalizing factor for these cells. It contains endosomolytic means which is a free of bound virus or viral component or one viral or non-viral peptide having endosomolytic properties. 117 claims
申请公布号
BG62740(B1)
申请公布日期
2000.06.30
申请号
BG19940098718
申请日期
1994.04.14
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
发明人
CURIEL, DAVID;WAGNER, ERNST;COTTEN, MATT;ZATLOUKAL, KURT;PLANK, CHRISTIAN;BIRNSTIEL, MAX L.;OBERHAUSER, BERND;SCHMIDT, WALTER G.
