发明名称 |
Tricyclic compounds and uses thereof |
摘要 |
Substituted isoquinolines, isochromanones and isothiochromanones that inhibit the pro-inflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and/or interleukin-6 (IL-6) and/or the enzyme cyclooxygenase-2 (COX-2) and/or interleukin-10 (IL-10). Compositions containing such compounds and methods of using such compounds for treatment and/or prevention of inflammation, inflammatory diseases, immunologic diseases and other diseases mediated by TNF-alpha, IL-6, COX-2 and/or IL-10 are also disclosed. |
申请公布号 |
AU1162102(A) |
申请公布日期 |
2002.04.22 |
申请号 |
AU20020011621 |
申请日期 |
2001.10.10 |
申请人 |
CALYX THERAPEUTICS, INC. |
发明人 |
DEBENDRANATH DEY;PARTHA NEOGI;ANANDA SEN;SOMESH D. SHARMA;BISHWAJIT NAG |
分类号 |
A61K31/352;A61K31/382;A61K31/472;A61P1/00;A61P5/14;A61P7/00;A61P9/08;A61P9/10;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/00;A61P19/02;A61P19/10;A61P21/00;A61P25/00;A61P27/02;A61P29/00;A61P31/00;A61P31/18;A61P33/06;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D217/16;C07D217/24;C07D311/76;C07D335/06 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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