摘要 |
The disclosure relates to compounds of Formula (1)and pharmaceutically acceptable salts of such compounds, wherein Z, Z, Z, X, X, X, Y, Xand Xhave the meanings defined in the claims, compositions comprising an effective amount of a compound of Formula (1) or a pharmaceutically acceptable salt of said compound, and methods to treat or prevent a disease, such as cancer which overexpresses Her-kinases, comprising administering to an patient in need thereof a therapeutically effective amount of a compound of Formula (1) or a pharmaceutically acceptable salt thereof. |