发明名称 NITRIC ESTER DERIVATIVES,PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUNDS AND METHOD OF USE THEREOF
摘要 A compound of the formula : <CHEM> wherein R<1> is hydrogen, lower alkyl, halo(lower)alkyl, halogen, aryl which may have suitable substituent(s), heterocyclic group, amino which may be substituted by suitable substituent(s) or N,N-di(lower)alkylamino(lower)alkyl, R<2> is hydrogen, lower alkyl or N-[nitrooxy(lower)alkyl]carbamoyl, X is -O- or -S-, Y is a single bond, lower alkylene or lower alkenylene, and Z is lower alkylene which may be substituted by suitable substituent(s) or lower alkyleneoxy(lower)alkylene, and pharmaceutically acceptable salts thereof, which have vasodilating activities, to process for the preparation thereof, and to a pharmaceutical composition comprising the same for therapeutical treatment of cardiovascular disorder in human being.
申请公布号 PH24481(A) 申请公布日期 1990.07.18
申请号 PH19590000371 申请日期 1988.07.01
申请人 FUJISAWA PHARMACEUTICAL CO.,LTD. 发明人 YOUICHI SHIOKAWA;KOHEI TAKENAKA;KOICHI TAKIMOTO
分类号 C07D277/20;A61K31/42;A61K31/421;A61K31/425;A61K31/426;A61K31/427;A61K31/44;A61K31/535;A61K31/5377;A61P9/08;A61P9/10;A61P9/12;C07D213/78;C07D263/32;C07D263/34;C07D263/48;C07D277/30;C07D277/40;C07D277/42;C07D277/46;C07D277/48;C07D277/56;C07D295/125;C07D413/04;C07D417/04 主分类号 C07D277/20
代理机构 代理人
主权项
地址
您可能感兴趣的专利