NEW PEPTIDE

摘要

PURPOSE:To provide a new peptide effective as an agent for preventing or treating AIDS and free from the troubles of side actions such as the function depression of normal lymphocytes and immunogenicity. CONSTITUTION:The peptide comprises an amino acid sequence on which a complemental DNA base sequence corresponding to a DNA base sequence coding gp 120 that is an outer skin protein of HIV is encoded in the direction of 5' 3' or 3' 5', and contains an amino acid sequence encoded with a complemental DNA base sequence corresponding to a DNA base sequence coding at least the amino acids at the 426-437 positions among the amino acid sequence of the gp 120. A peptide produced by replacing cysteine in the amino acid sequence of the peptide with serine, and its salt.