MUMBAISTATIN, A PROCESS FOR ITS PRODUCTION AND ITS USE AS A PHARMACEUTICAL

摘要

The present invention relates to a compound named Mumbaistatin which is obtainable by cultivation of the microorganism HIL-008003 (DSM 11641), and t o its pharmaceutically acceptable salts and derivatives. Mumbaistatin is a glucose-6-phosphate translocase inhibitor and can be used in the treatment o f diabetes mellitus. The present invention further relates to a process for th e production of Mumbaistatin, to the microorganism HIL-008003 (DSM 11641), to the use of Mumbaistatin and its pharmaceutically acceptable salts and derivatives as pharmaceuticals, in particular to their use in the treatment of diabetes mellitus, and to pharmaceutical compositions comprising Mumbaistati n or a pharmaceutically acceptable salt or derivative thereof.