发明名称 USE OF ANDROGEN RECEPTOR SUPPRESSORS
摘要 Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamido and haloarylamino derivatives thereof, as well as radiolabeled derivatives thereof. The compounds bind specifically to the androgen receptor and find use in indication associated with the androgen receptor, such as cell hyperplasia dependent on androgens, hirsutism, acne and androgenetic alopecia.
申请公布号 WO0037430(A2) 申请公布日期 2000.06.29
申请号 WO1999US26862 申请日期 1999.11.12
申请人 BIOPHYSICA, INC. 发明人 SOVAK, MILOS;SELIGSON, ALLEN, L.;DOUGLAS, JAMES, GORDON, III;CAMPION, BRIAN;BROWN, JASON, W.
分类号 A61K31/165;A61P5/00;C07C237/04;C07C255/56;C07C255/60;C07C275/30;C07C317/46;C07C323/60;C07C335/08;C07C335/16;C07C335/22;C07D207/40;C07D207/408;C07D233/72;C07D233/86;C07D233/88;(IPC1-7):C07C237/04;A61K31/16;A61K31/40;A61K31/415;C07C237/22;C07C317/48;C07D207/26;C07C235/22;C07D207/36;C07M5/00 主分类号 A61K31/165
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