发明名称 |
PROCESS FOR RECOVERING LIPOPHILIC OLIGOSACCHARIDE ANTIBIOTICS |
摘要 |
A process for recovering a lipophilic oligosaccharide antibiotic from an aqueous fermentation broth containing the lipophilic oligosaccharide antibiotic admixed with impurities, by-products and/or suspended solids, comprising: a) combining said fermentation broth with an adsorbent; b) adjusting the pH of the broth to alkaline in order to solubilize the antibiotic in the broth; c) allowing sufficient time for the solubilized antibiotic in the alkaline broth to be adsorbed by the adsorbent; d) adjusting the pH of the broth to about neutral in order to stabilize the antibiotic adsorbed on the adsorbent; and e) separating the adsorbent to which the antibiotic is adsorbed from the broth. A medium for storing an oligosaccharide antibiotic comprising an adsorbent having a lipophilic oligosaccharide antibiotic adsorbed thereon is also disclosed.
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申请公布号 |
WO0037670(A1) |
申请公布日期 |
2000.06.29 |
申请号 |
WO1999US27937 |
申请日期 |
1999.12.16 |
申请人 |
SCHERING CORPORATION |
发明人 |
ALROY, YAIR;BLAISDELL, STEVEN;MORENBERG, ALLAN;SCHAEFER, EUGENE |
分类号 |
C12P19/60;(IPC1-7):C12P19/60;C12N1/20;C12P19/04;C12S3/02 |
主分类号 |
C12P19/60 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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